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The gut microbiome and autoimmunity: How our gut bacteria influence the immune system 🔬 Send us Fan Mail
Keywords:
Gut Microbiome, Autoimmunity, Lupus, Microbiome Research, Enterococcus gallinarum, Immunological Tolerance, Microbiome Therapies
Summary:
In this episode of the Young Immunologist Podcast ImmunoChat, Pia Madeleine Leipe talk
Länge: 43:59
Send us Fan Mail
Keywords:
Gut Microbiome, Autoimmunity, Lupus, Microbiome Research, Enterococcus gallinarum, Immunological Tolerance, Microbiome Therapies
Summary:
In this episode of the Young Immunologist Podcast ImmunoChat, Pia Madeleine Leipe talks with Carina Brune about the role of the gut microbiome in the immune system and its connection to autoimmune diseases. They discuss the importance of gut microbes, the challenges in researching autoimmune diseases, and the potential therapeutic approaches emerging from microbiome research.
Takeaways:
The gut microbiome plays a crucial role in regulating the immune system.Dysbiosis in the microbiome can lead to autoimmune diseases.Enterococcus gallinarum is a bacterium linked to the development of lupus.Future therapies may target microbiome modulation, including vaccines and phage therapy.Please find here links to publications referred to in this Episode:
General Info:
Family size, infection and atopy: the first decade of the 'hygiene hypothesis' | ThoraxHost–microbiota interactions in immune-mediated diseases | Nature Reviews MicrobiologySLE and microbiome:
Translocation of a gut pathobiont drives autoimmunity in mice and humans | ScienceWithin-host evolution of a gut pathobiont facilitates liver translocation | NatureTranslocating gut pathobiont Enterococcus gallinarum induces TH17 and IgG3 anti-RNA–directed autoimmunity in mouse and human | Science Translational MedicineLupus and inflammatory bowel disease share a common set of microbiome features distinct from other autoimmune disorders | Annals of the Rheumatic Diseases Phage therapy
Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation: CellYouTube Video
Hinter den Kulissen des Tierlaboratoriums der Medizinischen Hochschule Hannover
Contact details
Carina Brune – University of Münster | LinkedIn
Immune-Microbiota Interactions Lab (@agkriegel.bsky.social) — Bluesky
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The Podcast is hosted by Pia Madeleine Leipe -
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Erscheinungsdatum: 28.4.2026, 19:00:00
